Precision Oncology: Rajen Mody, MD on genetic sequencing for childhood cancer

Precision Oncology: Rajen Mody, MD on genetic sequencing for childhood cancer


>>Over the last decade, we
have made great strides in terms of improving the survival for kids with cancer. However, kids who present with
metastatic disease and in whom, the first-line treatment does not work. Survival has not changed
for the last four decades and we really needed to do something different. In this kind of patients,
we deployed a new sequence in technology using the precision oncology
approach where we sequence the tumor DNA, the RNA, as well as normal DNA
to really look for new answers for these patients where all standard therapy had failed. And what we found in our study that
nearly half of these patients we were able to find actionable findings which informed
the treating physicians about new treatment or new diagnosis or new risk stratification or
new way to counsel the patient’s families. In quarter of these families, we were able
to actually take actions in these patients. In 10% of these cases, this changing
treatment resulted into durable partial or complete responses, and
patient benefitted clinically. [ Music ]

1 thought on “Precision Oncology: Rajen Mody, MD on genetic sequencing for childhood cancer”

  1. Several kids including my son are counting on such progress. God bless the doctors and researchers who work everyday tirelessly.

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